Ruizhi Chemical I Ruizhi Industries
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Website: www.RuizhiChem.com
Polyvinylpyrrolidone K Series
PVP K
Product name: Povidone
USP name: Povidone
EP name: Povidonum
INCI/CTFA: Polyvinylpyrrolidone(PVP)
CAS No.: 9003-39-8
Properties: Nontoxic; Non-irritant; Hygroscopic;
Freely soluble in water, alcohol and most other organic solvvents;
Very slightly soluble in acetone
Excellent solubility; Film-forming; Chemical stability;
Physiologically inert; Complexation and binding property.
Specification: Based on the polymer molecular weight and viscosity in water, the current series products are classified based on their K-values.
Product | K-Value* | Mv** | Main application |
K12 | 10.2-13.8 | 3,000-7,000 | Used as a solubilizer, dispersant and anti-crystallization agent in liquid dosage applications. |
K15 | 12.75-17.25 | 8,000-12,000 | |
K17 | 15.3-18.36 | 10,000-16,000 | |
K25 | 22.5-27.0 | 30,000-40,000 | Used as a binder, film-forming agent, solubilizer, suspension stabilizer and dispersant in dosage form applications. |
K30 | 27-32.4 | 45,000-58,000 | |
K60 | 54-64.8 | 270,000-400,000 | Used as a binder, thickener or suspension stabilizrer in dosage form applications. |
K90 | 81-97.2 | 1,000,000-1,500,000 | |
*K-value is calculated by viscosity of 1% water solution, also can be used to calculate Mv through Mark-Houwink formulation. **Mv is viscosity-average molecular weight. |
The addition of PVP K30 to HPMC film coating solutions can effectively reduce the viscosity of the HPMC solution while not affecting the resultant hydration profile of the resultant film.
| Puerarin povidone solid dispersions dissolution curve
Puerarin - PVP K30 solid dispersions can accelerate the dissolution of puerarin rate significantly. |
Applications:
PVP pharmaceutical grade:
CP2005/USP26/USP31/USP38/EP6/EP8/BP2007/BP2012
PVP K12 / PVP K15 / PVP K17 / PVP K25 / PVP K30 / PVP K60 / PVP K90
PVP Cosmetic grade
PVP K17 Powder
PVP K17 40% solution
PVP K30 Powder
PVP K30 30% solution
PVP K60 Powder
PVP K60 40% solution
PVP K90 Powder
PVP K90 20% solution
PVP Technical grade
PVP K17 Powder
PVP K17 40% solution
PVP K30 Powder
PVP K30 30% solution
PVP K60 Powder
PVP K60 40% solution
PVP K85 20% solution
PVP K90 Powder
PVP K90 20% solution
PVP (Polyvinylpyrrolidone) can be used in following industries:
Pharmaceuticals Industry
PVK K series have excellent adhesive, film-forming, dispersing and thickening properties, and can be used as binder of tablets, solubilizers, dispersant or coprecipitator agent, suspension stabilizer, Film/sugar coatings, film formers, thickening agents, Pore-former, release agent, capsule shell, etc. For example:
Dosage form | PVP ingredient |
Tablet | PVP-K30 |
Grain | PVP-K30 |
Coating agent | PVP-K30 |
Capsule | PVP-K30 |
Coprecipitation agent | PVP-K15 |
Injection | PVP-K15 |
Oral liquid | PVP-K15, K60 |
Pills | PVP-K30, K90 |
Disinfectant | PVP-I |
Lozenge | PVP-K30, K6 |
Daily chemical industry
Cosmetics Industry:
Hair spray, mousse, hair conditioner, shampoo, hair dye, hair-waving agent, cream, sunscreen cream, chilblain cream, shaving cream, depilatory, deodorant, mascara, nail enamel, lipstick, night cream, etc…
Cleaning products:
Toothpaste, perfumed soaps, medicated soaps, etc…
Disinfection industry
PVP-I used in health care to disinfect: skin, wound, mucosa, oral cavity, vagina
PVP-I used in food and catering Hygiene to disinfect: tableware, sanitary ware, Litchi, Vegetables, refrigerator, Food processing machinery, drinking water, Swimming Pool, Slaughterhouse, Beverage packaging equipment…
PVP-I used in aquaculture: prevention and treatment of disease for fish, crab, shrimp, feed disinfection, egg disinfection, disinfection of livestock and poultry…
Food and beverage industry
PVP used in vintage to remove polyphenols
PVPP used as stabilizer to treat Beer and Yellow Wine to increase the shelf life.
PVPP used in non-alcoholic beverages as clarifying agent and stabilizer
Office supplies
PVP used in ink
PVP used in paper
PVP use in gluewater
Coating & pigments
PVP used in organic pigments
PVP used in paint coating
Printing and dyeing industry
PVP used in printing and dyeing
Chemical reaction and chemical analysis
PVP used in polymerization
PVP used in chemical analysis and catalyst
New material
PVP used in barrier separation
PVP used as cement adhesive
PVP used as adhesive of glass, plastic
PVP used in conductive material, membrane materials
Other industry
In corrosion and corrosion of Iron, aluminum equipments
As emulsion stabilizer for Silver halide
Use PVP solution on the seed soaking to reduce the damage
Mix PVP and explosive liquid propellant to get solid or pasty, and easy to transport and storage.